AHCY antibody (N-Term)

Catalog No. ABIN950286

The Rabbit Polyclonal anti-AHCY antibody (ABIN950286) specifically detects AHCY in WB, IHC (p) and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for AHCY antibody (N-Term) (ABIN950286)

Target: AHCY (Adenosylhomocysteinase (AHCY))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHCY antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-AHCY Antibody

Binding Specificity: AA 86-118, N-Term

Specificity: This antibody reacts to AdoHcyase.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 86-118 amino acids from the N-terminal region of human AHCY

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Alternative Name: AdoHcyase (AHCY)

Background: S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, SAHH

Gene ID: 191

NCBI Accession: NP_000678