CC2D1A
Reactivity: Human
IHC, IF (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
CC2D1A
(Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
Alternative Name
CC2D1A
Background
CC2D1A is a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.Synonyms: Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein, Five repressor element under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N