PD-1 antibody (Biotin)

Catalog No. ABIN951268

This Hamster Monoclonal antibody specifically detects PD-1 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for PD-1 antibody (Biotin) (ABIN951268)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This PD-1 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: J43

Product Details anti-PD-1 Antibody (Biotin)

Specificity: PD1 monoclonal antibody reacts with mouse PD-1 (programmed death-1), a 55 kDa member of the Ig superfamily that has been demonstrated to play a key role in the regulation of immune response and peripheral tolerance. PD1 is expressed on activated T and B lymphocytes.

Purification: Affinity chromatography on Protein G

Immunogen: PD-1 cDNA transfectant Donor: mouse ascites fluid Fusion Partner: Mouse myeloma P3U1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: CD279 / PD1

Background: Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

Gene ID: 18566

NCBI Accession: NP_032824

UniProt: Q02242

Pathways: Cancer Immune Checkpoints