TLR9 antibody (AA 26-300)

Catalog No. ABIN951280

This Rabbit Polyclonal antibody specifically detects TLR9 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TLR9 antibody (AA 26-300) (ABIN951280)

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TLR9 Antibody

Binding Specificity: AA 26-300

Specificity: This antibody detects Toll-like Receptor 9 (TLR9).

Cross-Reactivity (Details): Species reactivity (expected):Bovine (84 %), Cat (85 %), Dogs (83 %), Pig (84 %), Monkey (95 %).
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 26 and 300 of Human CD289(TLR9).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.71 mg/mL

Buffer: 0.1 M Tris-glycine, pH 7, 10 % Glycerol and 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for TLR9

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Alternative Name: CD289 / TLR9

Background: TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.Synonyms: Toll-like receptor 9, UNQ5798/PRO19605

Gene ID: 54106

NCBI Accession: NP_059138

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades