CD4 antibody (FITC)

Catalog No. ABIN951310

This Rat Monoclonal antibody specifically detects CD4 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD4 antibody (FITC) (ABIN951310)

Target: CD4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: CT-CD4

Product Details anti-CD4 Antibody (FITC)

Specificity: This antibody CL004F recognizes CD4 . Results for tissue distribution by Flow Cytometry analysis (Mouse strain BALB/c): Cell source Spleen T cells: Percentage of cells stained above control = 59.2 % Cell source Thymus: Percentage of cells stained above control = 93.4 % (Cell concentration = 1x106 cells per test, antibody concentration = 1.0 μg/106 cells, isotypic control FITC Rat IgG2a).

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gene ID: 12504

NCBI Accession: NP_038516

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events