Coagulation Factor IX antibody

Catalog No. ABIN951595

This Sheep Polyclonal antibody specifically detects Coagulation Factor IX in IHC (p), EIA and ID. It exhibits reactivity toward Human.

Quick Overview for Coagulation Factor IX antibody (ABIN951595)

Target: Coagulation Factor IX (F9)

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Coagulation Factor IX antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Product Details anti-Coagulation Factor IX Antibody

Specificity: Recognizes Human Factor IX as demonstrated by Immunodiffusion. A single positive reactivity band was observed with Normal Human Plasma. No reaction was observed against Factor IX-deficient plasma.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulfate Precipitation

Immunogen: Human Factor IX purified from plasma.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 10 mg/mL

Buffer: 0.01 M HEPES, pH 7.4, 0.1 M Sodium Chloride and 50 % Glycerol.

Preservative: Azide free

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Background: Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.Synonyms: Christmas factor, PTC, Plasma thromboplastin component

Gene ID: 2158

NCBI Accession: NP_000124