Factor VII antibody (Biotin)

Catalog No. ABIN951601

This Mouse Monoclonal antibody specifically detects Factor VII in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Factor VII antibody (Biotin) (ABIN951601)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Factor VII antibody is conjugated to Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AA-3

Product Details anti-Factor VII Antibody (Biotin)

Specificity: This antibody is specific for factor VII/VIIa (AA-3).

Cross-Reactivity (Details): Also reacts to: VIIa

Immunogen: Human Factor VII (AA-3) purified from plasma.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Background: Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator

Gene ID: 2155

NCBI Accession: NP_000122

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling