COPS8 antibody (N-Term)

Catalog No. ABIN951663

The Rabbit Polyclonal anti-COPS8 antibody (ABIN951663) specifically detects COPS8 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for COPS8 antibody (N-Term) (ABIN951663)

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-COPS8 Antibody

Binding Specificity: AA 1-30, N-Term

Specificity: This antibody reacts to COPS8.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human COPS8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for COPS8

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Alternative Name: COPS8

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.Synonyms: COP9 signalosome complex subunit 8, CSN8, JAB1-containing signalosome subunit 8, SGN8, Signalosome subunit 8

Molecular Weight: 23226 Da

Gene ID: 10920

NCBI Accession: NP_006701

Pathways: Cell Division Cycle