CXCR7 antibody (Chemokine (C-X-C Motif) Receptor 7) (AA 340-370)

Details for Product anti-CXCR7 Antibody No. ABIN951737, Supplier: Log in to see
Antigen
  • BEST:LD12308
  • CG3171
  • Dmel\\CG3171
  • LD12308
  • Tre-1
  • anon-WO0170980.16
  • anon-WO0170980.17
  • anon-WO0170981.1
  • sctt
  • tre-1
  • tre1
  • CMKOR1
  • CXC-R7
  • CXCR-7
  • CXCR7
  • GPR159
  • RDC-1
  • RDC1
  • AW541270
  • Cmkor1
  • Cxcr7
  • Rdc1
  • Trapped in endoderm 1
  • ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74
  • atypical chemokine receptor 3
  • Tre1
  • MmrVgp88
  • ACKR3
  • Ackr3
Alternatives
anti-Human CXCR7 antibody for Flow Cytometry
Epitope
AA 340-370, C-Term
45
27
26
14
13
11
11
11
10
6
5
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
200
106
76
7
7
6
6
4
4
4
4
3
1
1
1
1
1
1
1
Host
Rabbit
129
83
19
5
1
Clonality
Polyclonal
Conjugate
This CXCR7 antibody is un-conjugated
19
14
10
10
10
10
10
9
8
8
7
6
4
4
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
132
94
51
40
26
25
15
7
5
5
3
2
2
2
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide between 340-370 amino acids from the C-terminal region of human CMKOR1
Isotype Ig Fraction
Specificity This antibody reacts to CMKOR1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CXCR7 / GPR159 (CXCR7 Antibody Abstract)
Background CXCR7 encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq].Synonyms: C-X-C chemokine receptor type 7, CMKOR1, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, GPR-159, RDC1
Gene ID 57007
NCBI Accession NP_064707
Pathways Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 340-370), (C-Term) antibody (ABIN951737) CMKOR1 Antibody (C-term) flow cytometric analysis of U251 cells (right histogra...
Western Blotting (WB) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 340-370), (C-Term) antibody (ABIN951737) CMKOR1 Antibody (C-term) western blot analysis in U251 cell line lysates (35µg/...
Background publications Berahovich, Zabel, Penfold, Lewén, Wang, Miao, Gan, Pereda, Dias, Slukvin, McGrath, Jaen, Schall: "CXCR7 protein is not expressed on human or mouse leukocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 9, pp. 5130-9, 2010 (PubMed).

Watanabe, Penfold, Matsuda, Ohyanagi, Kaneko, Miyabe, Matsumoto, Schall, Miyasaka, Nanki: "Pathogenic role of CXCR7 in rheumatoid arthritis." in: Arthritis and rheumatism, Vol. 62, Issue 11, pp. 3211-20, 2010 (PubMed).

Hattermann, Held-Feindt, Lucius, Müerköster, Penfold, Schall, Mentlein: "The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects." in: Cancer research, Vol. 70, Issue 8, pp. 3299-308, 2010 (PubMed).

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