Desmocollin 3 antibody (C-Term)

Catalog No. ABIN951890

The Rabbit Polyclonal anti-Desmocollin 3 antibody is suitable to detect Desmocollin 3 in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for Desmocollin 3 antibody (C-Term) (ABIN951890)

Target: Desmocollin 3 (DSC3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmocollin 3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Desmocollin 3 Antibody

Binding Specificity: AA 821-850, C-Term

Specificity: This antibody recognizes Human and Mouse Desmocollin-3 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 821-850 amino acids from the C-terminal region of Human Desmocollin-3. Genename: DSC3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Desmocollin 3

Target: Desmocollin 3 (DSC3)

Alternative Name: Desmocollin-3

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.Synonyms: CDHF3, Cadherin family member 3, DSC3, DSC4, Desmocollin-4, HT-CP

Molecular Weight: 99969 Da

Gene ID: 1825

NCBI Accession: NP_001932