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Desmoglein 3 antibody (N-Term)
DSG3
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Desmoglein 3 Antibody
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Target
See all Desmoglein 3 (DSG3) Antibodies
Desmoglein 3 (DSG3)
Binding Specificity
All epitopes for Desmoglein 3 antibodies
AA 7-36, N-Term
Reactivity
All reactivities for Desmoglein 3 antibodies
Human
Host
All hosts for Desmoglein 3 antibodies
Rabbit
Clonality
All clonalities for Desmoglein 3 antibodies
Polyclonal
Conjugate
All conjugates for Desmoglein 3 antibodies
This Desmoglein 3 antibody is un-conjugated
Application
All applications for Desmoglein 3 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human Desmoglein-3 (N-term).
Purification
Affinity Chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of Human Desmoglein-3 Genename: DSG3
Isotype
Ig Fraction
Top Product
Discover our top product DSG3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Desmoglein 3
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Target
Desmoglein 3 (DSG3)
Alternative Name
Desmoglein-3 (DSG3 Products )
Synonyms
DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
Background
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA
Molecular Weight
107533 Da
Gene ID
1830
NCBI Accession
NP_001935
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