Desmoglein 3 antibody (N-Term)

Catalog No. ABIN951892

This Rabbit Polyclonal antibody specifically detects Desmoglein 3 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Desmoglein 3 antibody (N-Term) (ABIN951892)

Target: Desmoglein 3 (DSG3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Desmoglein 3 Antibody

Binding Specificity: AA 7-36, N-Term

Specificity: This antibody recognizes Human Desmoglein-3 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of Human Desmoglein-3 Genename: DSG3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Desmoglein 3

Target: Desmoglein 3 (DSG3)

Alternative Name: Desmoglein-3

Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA

Molecular Weight: 107533 Da

Gene ID: 1830

NCBI Accession: NP_001935