DPH1 antibody (C-Term)

Catalog No. ABIN951975

Product Details anti-DPH1 Antibody

Target: DPH1 (DPH1 Homolog (DPH1))

Binding Specificity: AA 383-412, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPH1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human DPH1 / OVAC1 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of Human DPH1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DPH1

Target: DPH1 (DPH1 Homolog (DPH1))

Abstract: DPH1 Products

Background: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].Synonyms: DPH1 homolog, DPH2L, DPH2L1, Diphthamide biosynthesis protein 1, Diphthamide biosynthesis protein 2 homolog-like 1, Ovarian cancer-associated gene 1 protein

Molecular Weight: 48805 Da

Gene ID: 1801

NCBI Accession: NP_001374