ECSIT antibody (C-Term)

Catalog No. ABIN952019

The Rabbit Polyclonal anti-ECSIT antibody has been validated for WB and EIA. It is suitable to detect ECSIT in samples from Human.

Quick Overview for ECSIT antibody (C-Term) (ABIN952019)

Target: ECSIT

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECSIT antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ECSIT Antibody

Binding Specificity: AA 395-425, C-Term

Specificity: This antibody recognizes Human ECSIT (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 395-425 amino acids from the C-terminal region of human ECSIT

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ECSIT

Target: ECSIT

Alternative Name: ECSIT

Background: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.Synonyms: ECSIT homolog (Drosophila), Evolutionarily conserved signaling intermediate in Toll pathway, SITPEC, Signaling intermediate in toll pathway evolutionarily conserved, mitochondrial

Molecular Weight: 49148 Da

Gene ID: 51295

NCBI Accession: NP_001135936

Pathways: TLR Signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome