GPER antibody (C-Term)
-
- Target See all GPER Antibodies
- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
-
Binding Specificity
- AA 345-375, C-Term
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GPER antibody is un-conjugated
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to GPER.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human and Mouse.
- Purification
- Affinity chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human GPER
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GPER Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
- Alternative Name
- GPER / GPR30 (GPER Products)
- Background
- This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq].Synonyms: CEPR, CMKRL2, Chemoattractant receptor-like 2, DRY12, FEG1, Flow-induced endothelial G-protein coupled receptor 1, G-protein coupled estrogen receptor 1, G-protein coupled receptor 30, GPCR-BR, IL8-related receptor DRY12, LYGPR, Lymphocyte-derived G-protein coupled receptor
- Molecular Weight
- 42248 Da
- Gene ID
- 2852
- NCBI Accession
- NP_001035055
- Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
-