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Hepcidin antibody (Middle Region)
HAMP
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Hepcidin Antibody
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Target
See all Hepcidin (HAMP) Antibodies
Hepcidin (HAMP)
(Hepcidin Antimicrobial Peptide (HAMP))
Binding Specificity
All epitopes for Hepcidin antibodies
AA 24-54, Middle Region
Reactivity
All reactivities for Hepcidin antibodies
Human
Host
All hosts for Hepcidin antibodies
Rabbit
Clonality
All clonalities for Hepcidin antibodies
Polyclonal
Conjugate
All conjugates for Hepcidin antibodies
This Hepcidin antibody is un-conjugated
Application
All applications for Hepcidin antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human Hepcidin / HAMP (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 24~54 amino acids from the Central region of Human Hepcidin / HAMP
Isotype
Ig Fraction
Top Product
Discover our top product HAMP Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Hepcidin
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Target
Hepcidin (HAMP)
(Hepcidin Antimicrobial Peptide (HAMP))
Alternative Name
Hepcidin / HAMP (HAMP Products )
Background
HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor
Molecular Weight
9408 Da
Gene ID
57817
NCBI Accession
NP_066998
Pathways
Hormone Activity , Transition Metal Ion Homeostasis
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