HNF1B antibody (C-Term)

Catalog No. ABIN952765

This Rabbit Polyclonal antibody specifically detects HNF1B in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for HNF1B antibody (C-Term) (ABIN952765)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HNF1B Antibody

Binding Specificity: AA 505-536, C-Term

Specificity: This antibody recognizes Human HNF1 beta / TCF2 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 505-536 amino acids from the C-terminal region of human HNF1B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Alternative Name: HNF1 beta / TCF2

Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this geneSynonyms: HNF-1-beta, HNF-1B, Hepatocyte nuclear factor 1-beta, LFB3, TCF-2, Transcription factor 2, Variant hepatic nuclear factor 1, vHNF1

Molecular Weight: 61324 Da

Gene ID: 6928

NCBI Accession: NP_000449

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation