INSC antibody (C-Term)

Catalog No. ABIN952909

This Rabbit Polyclonal antibody specifically detects INSC in WB, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for INSC antibody (C-Term) (ABIN952909)

Target: INSC (Inscuteable Homolog (INSC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-INSC Antibody

Binding Specificity: AA 416-445, C-Term

Specificity: This antibody recognizes Human and Mouse INSC (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 416-445 amino acids from the C-terminal region of human INSC

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for INSC

Target: INSC (Inscuteable Homolog (INSC))

Alternative Name: INSC

Background: In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).Synonyms: Protein inscuteable homolog

Molecular Weight: 63469 Da

Gene ID: 387755

NCBI Accession: NP_001027024