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KREMEN2 antibody (Middle Region)

KREMEN2 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN953114
  • Target See all KREMEN2 Antibodies
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 247-276, Middle Region
    Reactivity
    • 19
    • 17
    • 16
    Human
    Host
    • 31
    • 3
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KREMEN2 antibody is un-conjugated
    Application
    • 34
    • 18
    • 13
    • 13
    • 3
    • 3
    • 3
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to KREMEN2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KREMEN2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Alternative Name
    Kremen Protein 2 (KREMEN2 Products)
    Synonyms
    krm2 antibody, KREMEN2 antibody, MGC147633 antibody, KRM2 antibody, 2900054E04Rik antibody, Krm2 antibody, kringle containing transmembrane protein 2 S homeolog antibody, kringle containing transmembrane protein 2 antibody, kremen2.S antibody, KREMEN2 antibody, kremen2 antibody, Kremen2 antibody
    Background
    This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.Synonyms: Dickkopf receptor 2, KREMEN2, KRM2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose
    Gene ID
    79412
    NCBI Accession
    NP_078783
    Pathways
    WNT Signaling
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