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MCM7 antibody (N-Term)
MCM7
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MCM7 Antibody
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Target
See all MCM7 Antibodies
MCM7
(Minichromosome Maintenance Complex Component 7 (MCM7))
Binding Specificity
All epitopes for MCM7 antibodies
AA 113-142, N-Term
Reactivity
All reactivities for MCM7 antibodies
Human
Host
All hosts for MCM7 antibodies
Rabbit
Clonality
All clonalities for MCM7 antibodies
Polyclonal
Conjugate
All conjugates for MCM7 antibodies
This MCM7 antibody is un-conjugated
Application
All applications for MCM7 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human MCM7 (N-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human MCM7
Isotype
Ig Fraction
Top Product
Discover our top product MCM7 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MCM7
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Target
MCM7
(Minichromosome Maintenance Complex Component 7 (MCM7))
Alternative Name
MCM7 (MCM7 Products )
Synonyms
CDC47 antibody, MCM2 antibody, P1.1-MCM3 antibody, P1CDC47 antibody, P85MCM antibody, PNAS146 antibody, MCM7 antibody, AI747533 antibody, Mcmd7 antibody, mCDC47 antibody, chunp6911 antibody, nyz175 antibody, sr:nyz175 antibody, cdc47 antibody, cdc47-2 antibody, mcm7 antibody, xmcm7 antibody, CG4978 antibody, DmMCM7 antibody, DmeMCM7 antibody, Dmel\\CG4978 antibody, McM7 antibody, Mcp-PCR1 antibody, PCR1 antibody, anon-EST:Liang-1.66 antibody, clone 1.66 antibody, minichromosome maintenance complex component 7 antibody, mini-chromosome maintenance complex protein 7 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 7 L homeolog antibody, Minichromosome maintenance 7 antibody, minichromosome maintenance complex component 7 S homeolog antibody, MCM complex subunit Mcm7 antibody, MCM7 antibody, CDC47 antibody, Mcm7 antibody, MCM2 antibody, mcm7 antibody, mcm7.L antibody, mcm7.S antibody
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Synonyms: CDC47, CDC47 homolog, DNA replication licensing factor MCM7, MCM2, P1.1-MCM3, minichromosome maintenance complex component 7
Molecular Weight
81308 Da
Gene ID
4176
NCBI Accession
NP_005907
Pathways
DNA Damage Repair , Mitotic G1-G1/S Phases , DNA Replication , Chromatin Binding , Synthesis of DNA
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