MEF2A antibody (Middle Region)

Catalog No. ABIN953380

This Rabbit Polyclonal antibody specifically detects MEF2A in WB, IF, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for MEF2A antibody (Middle Region) (ABIN953380)

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MEF2A Antibody

Binding Specificity: AA 459-488, Middle Region

Specificity: This antibody recognizes Human and Mouse MEF2A (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 459~488 amino acids from the Center region of human MEF2A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Alternative Name: MEF2A

Background: MEF2A is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this protein could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1).Synonyms: MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

Molecular Weight: 54811 Da

Gene ID: 4205

NCBI Accession: NP_001124398

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades