MUTYH antibody (Middle Region)

Catalog No. ABIN953552

The Rabbit Polyclonal anti-MUTYH antibody has been validated for WB, IF, FACS and EIA. It is suitable to detect MUTYH in samples from Human and Mouse.

Quick Overview for MUTYH antibody (Middle Region) (ABIN953552)

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUTYH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-MUTYH Antibody

Binding Specificity: AA 352-381, Middle Region

Specificity: This antibody recognizes MUTYH.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 352-381aa) of human MUTYH.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Alternative Name: MUTYH

Background: MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog

Gene ID: 4595

NCBI Accession: NP_001041636

Pathways: DNA Damage Repair