BTBD14A antibody (C-Term)
-
- Target See all BTBD14A Antibodies
- BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
-
Binding Specificity
- AA 472-502, C-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This BTBD14A antibody is un-conjugated
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human NACC2 / BTBD14A (C-term).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 472-502 amino acids from the C-terminal region of human NACC2 / BTBD14A
- Isotype
- Ig Fraction
- Top Product
- Discover our top product BTBD14A Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- BTBD14A (BTB (POZ) Domain Containing 14A (BTBD14A))
- Alternative Name
- NACC2 / BTBD14A (BTBD14A Products)
- Synonyms
- NACC2 antibody, BTBD14A antibody, BEND9 antibody, BTBD14 antibody, BTBD31 antibody, Btbd14a antibody, 0610020I02Rik antibody, AI448087 antibody, C030048H19Rik antibody, NACC family member 2 antibody, nucleus accumbens-associated protein 2-like antibody, nucleus accumbens associated 2, BEN and BTB (POZ) domain containing antibody, NACC2 antibody, LOC100354269 antibody, Nacc2 antibody
- Background
- BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.Synonyms: BTB/POZ domain-containing protein 14A, Nucleus accumbens-associated protein 2
- Molecular Weight
- 62837 Da
- Gene ID
- 138151
- NCBI Accession
- NP_653254
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
-