NCALD antibody (C-Term)
Quick Overview for NCALD antibody (C-Term) (ABIN953613)
Target
See all NCALD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 154-182, C-Term
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Specificity
- This antibody recognizes Human and Mouse NCALD (C-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human NCALD
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NCALD (Neurocalcin delta (NCALD))
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Alternative Name
- NCALD
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Background
- NCALD encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels, however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein, additional variants may exist but their biological validity has not been determined.Synonyms: Neurocalcin-delta
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Molecular Weight
- 22245 Da
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Gene ID
- 83988
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NCBI Accession
- NP_001035714
Target
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