NFS1 antibody (Middle Region)

Catalog No. ABIN953697

The Rabbit Polyclonal anti-NFS1 antibody (ABIN953697) specifically detects NFS1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for NFS1 antibody (Middle Region) (ABIN953697)

Target: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFS1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-NFS1 Antibody

Binding Specificity: AA 120-149, Middle Region

Specificity: This antibody recognizes human NFS1.

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 120-149aa) of human NFS1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NFS1

Target: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Alternative Name: NFS

Background: Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH . The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.Synonyms: Cysteine desulfurase, HUSSY-08, NIFS

Molecular Weight: 50196 Da

Gene ID: 9054

NCBI Accession: NP_001185918

Pathways: Transition Metal Ion Homeostasis