PAPOLA antibody (Middle Region)

Catalog No. ABIN953985

The Rabbit Polyclonal anti-PAPOLA antibody (ABIN953985) specifically detects PAPOLA in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for PAPOLA antibody (Middle Region) (ABIN953985)

Target: PAPOLA (Poly(A) Polymerase alpha (PAPOLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPOLA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PAPOLA Antibody

Binding Specificity: AA 414-443, Middle Region

Specificity: This antibody recognizes Human PAPOLA (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 414-443 amino acids from the Central region of human PAPOLA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PAPOLA

Target: PAPOLA (Poly(A) Polymerase alpha (PAPOLA))

Alternative Name: PAPOLA

Background: Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.Synonyms: PAP-alpha, Poly(A) polymerase alpha, Polynucleotide adenylyltransferase alpha

Molecular Weight: 82843 Da

Gene ID: 10914

NCBI Accession: NP_116021