PAX6 antibody

Catalog No. ABIN954011

The Rabbit Polyclonal anti-PAX6 antibody has been validated for WB, IF and EIA. It is suitable to detect PAX6 in samples from Human.

Quick Overview for PAX6 antibody (ABIN954011)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-PAX6 Antibody

Specificity: This antibody reacts to PAX6.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: Recombinant protein from human PAX6

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6

Background: This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6

Molecular Weight: 46683 Da

Gene ID: 5080

NCBI Accession: NP_000271

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis