PEX12 antibody (Middle Region)

Catalog No. ABIN954095

Product Details anti-PEX12 Antibody

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Binding Specificity: AA 137-167, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX12 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse Peroxin 12 / PEX12 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 137~167 amino acids from the Central region of human PEX12

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PEX12

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Alternative Name: Peroxin 12 / PEX12 (PEX12 Products)

Background: Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.Synonyms: PAF-3, PAF3, Peroxin-12, Peroxisome assembly factor 3, Peroxisome assembly protein 12

Molecular Weight: 40797 Da

Gene ID: 5193

NCBI Accession: NP_000277