SEC61B antibody (Middle Region)

Catalog No. ABIN954705

The Rabbit Polyclonal anti-SEC61B antibody (ABIN954705) specifically detects SEC61B in WB and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SEC61B antibody (Middle Region) (ABIN954705)

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SEC61B Antibody

Binding Specificity: AA 41-70, Middle Region

Specificity: Recognizes SEC61B (Center).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 41-70 amino acids from the Central region of Human SEC61B (NP_006799.1) Genename: SEC61B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SEC61B

Target: SEC61B (Sec61 beta Subunit (SEC61B))

Alternative Name: SEC61B

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.Synonyms: Protein transport protein Sec61 subunit beta

Gene ID: 10952

NCBI Accession: NP_006799

Pathways: Protein targeting to Nucleus