TAPBPL antibody (TAP Binding Protein-Like) (N-Term)

Details for Product anti-TAPBPL Antibody No. ABIN955075, Supplier: Log in to see
Antigen
  • TAPBPL
  • TAPBP-R
  • TAPBPR
  • BC017613
  • TAPBPL-R
  • Tapbplr
  • TAP binding protein like
  • TAP binding protein-like
  • TAPBPL
  • Tapbpl
Epitope
N-Term, AA 1-31
9
9
7
4
4
3
2
1
1
1
1
1
Reactivity
Human
54
5
4
4
3
2
2
1
1
1
1
1
Host
Rabbit
28
26
Clonality
Polyclonal
Conjugate
This TAPBPL antibody is un-conjugated
3
3
3
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
50
22
18
8
6
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 1-31 amino acids from the N-terminal region of human TAPBPL
Isotype Ig Fraction
Specificity This antibody reacts to TAPBPL.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Plasmids, Primers & others Plasmids, Primers & others TAPBPL products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Tapasin-Related Protein (TAPBPL) (TAPBPL Antibody Abstract)
Background Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP, see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.Synonyms: TAP-binding protein-like, TAP-binding protein-related protein, TAPASIN-R, TAPBP-R, Tapasin-like
Molecular Weight 50183 Da
Gene ID 55080
NCBI Accession NP_060479
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-TAP Binding Protein-Like (TAPBPL) (AA 1-31), (N-Term) antibody (ABIN955075) TAPBPL Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane)...
Background publications Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, 2009 (PubMed).

Chapuis, Hot, Hansmannel, Kerdraon, Ferreira, Hubans, Maurage, Huot, Bensemain, Laumet, Ayral, Fievet, Hauw, DeKosky, Lemoine, Iwatsubo, Wavrant-Devrièze, Dartigues, Tzourio, Buée, Pasquier, Berr et al.: "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. ..." in: Molecular psychiatry, Vol. 14, Issue 11, pp. 1004-16, 2009 (PubMed).

Lee, Cheng, Rogaeva, Meng, Stern, Santana, Lantigua, Medrano, Jimenez-Velazquez, Farrer, St George-Hyslop, Mayeux: "Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease." in: Neurogenetics, Vol. 9, Issue 2, pp. 127-38, 2008 (PubMed).

Zhang, Henzel: "Signal peptide prediction based on analysis of experimentally verified cleavage sites." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 10, pp. 2819-24, 2004 (PubMed).

Teng, Stephens, Du Pasquier, Freeman, Lindquist, Trowsdale: "A human TAPBP (TAPASIN)-related gene, TAPBP-R." in: European journal of immunology, Vol. 32, Issue 4, pp. 1059-68, 2002 (PubMed).

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