UPK1A antibody (C-Term)

Catalog No. ABIN955479

Cited in 1 publication. The Rabbit Polyclonal anti-UPK1A antibody (ABIN955479) specifically detects UPK1A in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for UPK1A antibody (C-Term) (ABIN955479)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-UPK1A Antibody

Binding Specificity: AA 197-227, C-Term

Specificity: This antibody detects Uroplakin-1a (UPK1A) (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 197~227 amino acids from the C-terminal region of human UPK1A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

References for anti-UPK1A antibody (ABIN955479)

Feenstra, Thøgersen, Wieser, Peschel, Ball, Brandes, Satchell, Stockner, Aarestrup, Rees, Kain: "Adhesion of Escherichia coli under flow conditions reveals potential novel effects of FimH mutations." in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Vol. 36, Issue 3, pp. 467-478, (2017) (PubMed).

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: Uroplakin-1a (UPK1A)

Background: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.Synonyms: TSPAN21, Tetraspanin-21, Tspan-21, UP1a, UPIa, UPKa, Uroplakin Ia

Gene ID: 11045

NCBI Accession: NP_008931