TNF alpha antibody

Catalog No. ABIN959542

This Mouse Monoclonal antibody specifically detects TNF alpha in WB, IHC, FACS, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Monkey and Guinea Pig.

Quick Overview for TNF alpha antibody (ABIN959542)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human, Mouse, Monkey, Guinea Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 52B83

Product Details anti-TNF alpha Antibody

Specificity: The antibody cross reacts with mouse, guinea pig and rhesus monkey TNF-alpha.

Purification: 0.2 Micron Filter

Immunogen: TNF-alpha

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr, IHC-P, WB

Usage: The monoclonal antibody can be used for Western blot and for staining of TNF-alpha in tissuesections of human, several monkeys and possibly also other animals. It stains both frozen sectionsand classic paraffin embedded sections. Unspecific background staining is seen in connective tissue.Is is also useful for immunoassays and flow cytometry.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS with 0.02 % Sodium azide and 0.1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF Alpha

Background: Name/Gene ID: TNF
Family: TNF

Synonyms: TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2

Gene ID: 7124

UniProt: P01375

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome