TLR4 antibody (Biotin)

Catalog No. ABIN960441

This anti-TLR4 antibody is a Mouse Monoclonal antibody detecting TLR4 in FACS, ELISA, IP and Neut. Suitable for Human and Dog.

Quick Overview for TLR4 antibody (Biotin) (ABIN960441)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Neutralization (Neut)

Clone: HTA125

Product Details anti-TLR4 Antibody (Biotin)

Specificity: The has been shown to block the activation of monocytes with LPS (Paik, et al, 2003).

Purification: Protein G purified

Immunogen: This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).

Type of Immunogen: Cells

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: ELISA (1 μg/mL), Flo (2 - 5 μg/10 x10⁶), IP, Neut

Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C, stable for 6 months. DO NOT FREEZE.

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: TLR4

Background: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins