TLR4 antibody (Biotin)

Catalog No. ABIN960441

The Biotin-conjugated Mouse Monoclonal anti-TLR4 antibody (Clone HTA125) (ABIN960441) specifically detects TLR4 in FACS, ELISA, IP and Neut. The antibody is reactive with Human and Dog samples.

Quick Overview for TLR4 antibody (Biotin) (ABIN960441)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Neutralization (Neut)

Clone: HTA125

Product Details anti-TLR4 Antibody (Biotin)

Specificity: The has been shown to block the activation of monocytes with LPS (Paik, et al, 2003).

Purification: Protein G purified

Immunogen: This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).

Type of Immunogen: Cells

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: ELISA (1 μg/mL), Flo (2 - 5 μg/10 x10⁶), IP, Neut

Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C, stable for 6 months. DO NOT FREEZE.

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: TLR4

Background: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins