TLR4 antibody

Catalog No. ABIN961106

The Mouse Monoclonal anti-TLR4 antibody has been validated for FACS, IP and Neut. It is suitable to detect TLR4 in samples from Human and Dog.

Quick Overview for TLR4 antibody (ABIN961106)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Neutralization (Neut)

Clone: HTA125

Product Details anti-TLR4 Antibody

Specificity: The has been shown to block the activation of monocytes with LPS (Paik, et al, 2003).

Purification: Protein G purified

Sterility: Sterile filtered

Immunogen: This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (2 - 5 μg/10 x10⁶), IP, Neut

Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, azide-free, sterile filtered

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: TLR4

Background: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins