MCM5 antibody
Quick Overview for MCM5 antibody (ABIN962070)
Target
See all MCM5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Brand
- IHC-plus™
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Specificity
- Recognizes human Mcm-5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46. Mcm5 is a nuclear protein of ~95kD with an important role in the control of DNA replication. It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy.
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Purification
- Protein G purified
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Immunogen
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Bacterially expressed human Mcm5.
Type of Immunogen: Recombinant protein -
Isotype
- IgG2b
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Application Notes
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Approved: IHC, IHC-P (10 μg/mL), WB
Usage: Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
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Alternative Name
- MCM5
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Background
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Name/Gene ID: MCM5
Synonyms: MCM5, CDC46, CDC46 homolog, p1-CDC46 -
Gene ID
- 4174
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UniProt
- P33992
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Pathways
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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