FBXW11 antibody (N-Term)

Catalog No. ABIN964575

Product Details anti-FBXW11 Antibody

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Cow, Chicken, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human ßTrCP2 protein.  A BLAST analysis was used to suggest cross-reactivity with ßTrCP2 from human, mouse, dog, bovine, chimpanzee, chicken and horse based on a 100% homology with the immunizing sequence.  Cross-reactivity with ßTrCP2 from other sources has not been determined.

Cross-Reactivity: Mouse (Murine), Dog (Canine), Chicken, Sheep (Ovine), Monkey

Characteristics: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Purification: purified

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminal of human ßTrCP2 protein.
Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and western blotting.

Comment:

Gene Name: FBXW11 (BTRCP2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Expiry Date: 12 months

Target Details for FBXW11

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Abstract: FBXW11 Products

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Synonyms: beta Transducin Repeat Containing Protein 2 antibody, BTRC2 antibody, BTRCP2 antibody, F-box and WD-40 Domain Protein 1B antibody, F-box Protein FBW1B antibody, FBW1B antibody, FBXW1B antibody

Gene ID: 23291, 48928048

UniProt: Q9UKB1