ASK1 antibody
Quick Overview for ASK1 antibody (ABIN965601)
Target
See all ASK1 (MAP3K5) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- ASK1 (Ab-966) antibody detects endogenous levels of total ASK1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human ASK1 around the phosphorylation site of serine 966 (S-I-SP-L-P).
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Application Notes
- IHC: 1:50-1:100.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100ug/100ul.
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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: "Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor." in: The Journal of biological chemistry, Vol. 280, Issue 19, pp. 19036-44, (2005) (PubMed).
: "Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation." in: The Journal of biological chemistry, Vol. 279, Issue 11, pp. 10442-9, (2004) (PubMed).
: "Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034." in: Oncogene, Vol. 23, Issue 29, pp. 5099-104, (2004) (PubMed).
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- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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Alternative Name
- ASK1
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Pathways
- MAPK Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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