(1 reference)-
- Target See all BLK Antibodies
- BLK (B Lymphoid Tyrosine Kinase (BLK))
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Reactivity
- Human
- Host
- Please inquire
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Clonality
- Monoclonal
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Conjugate
- This BLK antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3
- Purification
- Crude ascites.
- Isotype
- IgG2a
- Top Product
- Discover our top product BLK Primary Antibody
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anti-B Lymphoid Tyrosine Kinase (BLK) (AA 241-494) antibody
BLK Reactivity: Human WB, ELISA, IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) antibodyBLK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 7A12 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-30), (N-Term) antibodyBLK Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB03107 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 1-00E-06 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3E5-3A8 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D10B7 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibodyBLK Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibodyBLK Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) antibodyBLK Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 9D10D1 unconjugated
anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibodyBLK Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- -20 °C
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: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
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: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
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- Target
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- Alternative Name
- BLK (BLK Products)
- Synonyms
- bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody
- Background
- BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src nonreceptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
- Gene ID
- 640
- Pathways
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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