CD14 antibody

Catalog No. ABIN965766

This anti-CD14 antibody is a Monoclonal antibody detecting CD14 in IHC and ELISA. Suitable for Human.

Quick Overview for CD14 antibody (ABIN965766)

Target: CD14

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-CD14 Antibody

Specificity: Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein G affinity chromatography.

Isotype: IgG1

Application Details

Application Notes: IHC: Dilution 1:200-1:400
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.2%BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.

Gene ID: 929

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades