CD4 antibody

Catalog No. ABIN965794

This Monoclonal antibody specifically detects CD4 in WB, IHC and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CD4 antibody (ABIN965794)

Target: CD4

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CD4 Antibody

Specificity: Ni-NTA purified recombinant human CD4 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Western Blot, IHC and ELISA. Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-CD4 antibody (ABIN965794)

Benkirane, Hirn, Carrière, Devaux: "Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4." in: Journal of virology, Vol. 69, Issue 11, pp. 6898-903, (1995) (PubMed).

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells

Gene ID: 920

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events