CHEK2 antibody
(4 references)-
- Target See all CHEK2 Antibodies
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHEK2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- Chk2 (Ab-68) antibody detects endogenous levels of total Chk2 protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Chk2 around the phosphorylation site of threonine 68.
- Top Product
- Discover our top product CHEK2 Primary Antibody
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anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 1-220) antibodyCHEK2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibodyCHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibodyCHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibodyCHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibodyCHEK2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB19067 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibodyCHEK2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibodyCHEK2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4B7 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) antibodyCHEK2 Reactivity: Human, Monkey, Dog WB, IHC, IF, IHC (p), FACS Host: Mouse Monoclonal 10G7 unconjugated
anti-Checkpoint Kinase 2 (CHEK2) antibodyCHEK2 Reactivity: Human, Dog WB, IHC, IF, IHC (p), IP, FACS Host: Mouse Monoclonal 5C4 unconjugated
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- Application Notes
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WB: 1:500~1:1000
IHC: 1:50~1:100. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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: "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response." in: Molecular cell, Vol. 18, Issue 5, pp. 577-87, (2005) (PubMed).
: "Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions." in: Nature, Vol. 434, Issue 7035, pp. 907-13, (2005) (PubMed).
: "Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis." in: Oncogene, Vol. 24, Issue 12, pp. 1973-81, (2005) (PubMed).
: "Regulation of CHK2 by DNA-dependent protein kinase." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 12041-50, (2005) (PubMed).
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: "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response." in: Molecular cell, Vol. 18, Issue 5, pp. 577-87, (2005) (PubMed).
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- Target
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
- Alternative Name
- CHK2 (CHEK2 Products)
- Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle
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