Cytokeratin 19 antibody (C-Term)

Catalog No. ABIN965902

This Polyclonal antibody specifically detects Cytokeratin 19 in WB, IHC (p) and ICC. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for Cytokeratin 19 antibody (C-Term) (ABIN965902)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reactivity: Human

Host: Please inquire

Clonality: Polyclonal

Conjugate: This Cytokeratin 19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-Cytokeratin 19 Antibody

Binding Specificity: AA 379-392, C-Term

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human CK19 (379-392aa), identical to the related mouse and rat sequence.

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative: Thimerosal (Merthiolate), Sodium azide

Storage: -20 °C

References for anti-Cytokeratin 19 antibody (ABIN965902)

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Target Details for Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Alternative Name: CK19

Background: Cytokeratin-19 (CK-19) or keratin-19 (K19) is a protein that in humans is encoded by the KRT19 gene. Keratin 19 is a type I keratin. Keratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.