IL-11 antibody

Catalog No. ABIN966389

Product Details anti-IL-11 Antibody

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: Purified recombinant fragment of human IL-11 expressed in E. Coli.

Clone: 6D9A1

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Buffer: PBS

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-IL-11 antibody (ABIN966389)

Cockrell, Gorman, Hord,: "Endogenous interleukin-11 (IL-11) levels in newly diagnosed children with acquired severe aplastic anemia (SAA)." in: Cytokine, Vol. 28, Issue 2, pp. 55-8, (2004) (PubMed).

Target Details for IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Alternative Name: IL-11 (IL11 Products)

Synonyms: IL11 antibody, AGIF antibody, IL-11 antibody, Il-11 antibody, interleukin 11 antibody, IL11 antibody, Il11 antibody

Background: IL11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
Synonyms: AGIF, IL-11

Gene ID: 3589

Pathways: JAK-STAT Signaling, Negative Regulation of Hormone Secretion