IL1A antibody

Catalog No. ABIN966392

There is 1 publication for this product available. The Monoclonal anti-IL1A antibody is suitable to detect IL1A in samples from Human. It has been validated for WB and ELISA.

Quick Overview for IL1A antibody (ABIN966392)

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This IL1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL1A Antibody

Specificity: Ni-NTA purified recombinant human IL-1 alpha, expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG2a

Application Details

Application Notes: Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-IL1A antibody (ABIN966392)

Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." in: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL-1a

Background: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Gene ID: 3552

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints