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LSD1 antibody
There is 1 publication for this product available. The Monoclonal anti-LSD1 antibody is suitable to detect LSD1 in samples from Human. It has been validated for WB, IHC and ELISA.
Catalog No. ABIN966497
$522.50
Plus shipping costs $50.00
Delivery in 4 to 7 Business Days
Quick Overview for LSD1 antibody (ABIN966497)
Target
See all LSD1 (KDM1A) Antibodies
LSD1 (KDM1A)
(Lysine (K)-Specific Demethylase 1A (KDM1A))
Reactivity
All reactivities for LSD1 antibodies
Human
Host
Please inquire
Clonality
All clonalities for LSD1 antibodies
Monoclonal
Conjugate
All conjugates for LSD1 antibodies
This LSD1 antibody is un-conjugated
Application
All applications for LSD1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Product Details anti-LSD1 Antibody
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Specificity
Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3)
Purification
Crude Asites are purified by protein A affinity chromatography.
Isotype
IgG1
Alternatives
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Application Details
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Application Notes
Western Blot: 1: 500- 1: 2,000 IHC(P): 1: 500- 1: 2,000 IHC(F): 1: 500- 1: 2,000 ELISA: Propose dilution 1: 10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Storage
-20 °C
References for anti-LSD1 antibody (ABIN966497)
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Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle : "
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. " in:
Nature ,
Vol. 437 ,
Issue 7057 ,
pp. 436-9 , (
2005 ) (
PubMed ).
Target Details for LSD1
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Target
LSD1 (KDM1A)
(Lysine (K)-Specific Demethylase 1A (KDM1A))
Alternative Name
LSD1/AOF2
Background
The amine oxidase domain 2(AOF2)gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Gene ID
23028
Pathways
Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Negative Regulation of intrinsic apoptotic Signaling , Warburg Effect
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anti-LSD1 antibody (ABIN966497)
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