OTX2 antibody

Catalog No. ABIN966721

This Mouse Monoclonal antibody specifically detects OTX2 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for OTX2 antibody (ABIN966721)

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OTX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 1H12G8B2

Product Details anti-OTX2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human OTX2 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-OTX2 antibody (ABIN966721)

Adamson, Shi, Wortham, Northcott, Di, Duncan, Li, McLendon, Bigner, Taylor, Yan: "OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas." in: Cancer research, Vol. 70, Issue 1, pp. 181-91, (2010) (PubMed).

Target Details for OTX2

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Alternative Name: OTX2

Background: This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.
Tissue specificity: Expressed in brain.
Synonyms: MCOPS5, MGC45000

Molecular Weight: 32kDa

Gene ID: 5015

Pathways: Dopaminergic Neurogenesis