SCD antibody

Catalog No. ABIN966997

This Monoclonal antibody specifically detects SCD in WB, ELISA, IHC and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for SCD antibody (ABIN966997)

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Reactivity: Human, Mouse

Host: Please inquire

Clonality: Monoclonal

Conjugate: This SCD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-SCD Antibody

Specificity: Full length recombinant protein. Reacts with human and mouse proteins.

Isotype: IgG2b

Application Details

Application Notes: Western blot, ELISA, IP, and IHC in obesity research.

Restrictions: For Research Use only

Handling

Concentration: 1mg/ml

Buffer: PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SCD

Target: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Alternative Name: SCD1

Background: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.

Gene ID: 20249

Pathways: Brown Fat Cell Differentiation