Survivin antibody

Catalog No. ABIN967116

Cited in 1 publication. The Mouse Monoclonal anti-Survivin antibody (Clone 2H5H2) (ABIN967116) specifically detects Survivin in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Survivin antibody (ABIN967116)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2H5H2

Product Details anti-Survivin Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of SYT1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Survivin antibody (ABIN967116)

Xu, Gammon, Zeisel, Lee, Wetmur, Teitelbaum, Bradshaw, Neugut, Santella, Chen: "Choline metabolism and risk of breast cancer in a population-based study." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 6, pp. 2045-52, (2008) (PubMed).

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: Survivin

Background: SYT1: synaptotagmin I. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.
Synonyms: API4, EPR-1, BIRC5

Gene ID: 332

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding