SELPLG antibody

Catalog No. ABIN967489

This Mouse Monoclonal antibody specifically detects SELPLG in FACS, WB, IP and BR. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for SELPLG antibody (ABIN967489)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SELPLG antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Blocking Reagent (BR)

Clone: KPL-1

Product Details anti-SELPLG Antibody

Brand: BD Pharmingen™

Characteristics: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility: 0.2 μm filtered

Endotoxin Level: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-SELPLG antibody (ABIN967489)

Snapp, Ding, Atkins, Warnke, Luscinskas, Kansas: "A novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition of both P- and L-selectin." in: Blood, Vol. 91, Issue 1, pp. 154-64, (1998) (PubMed).

Target Details for SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: CD162

Background: Reacts with p-selectin glycoprotein ligand-1 (PSGL-1), a 120 - 220 kDa, mucin-like type I transmembrane glycoprotein. CD162 is expressed on neutrophils, monocytes, and most lymphocytes. CD162 binds to CD62P (P-Selectin), CD62E (E-Selectin) and CD62L (L-Selectin). This molecule mediates rolling of leukocytes on activated endothelium and the interaction between leukocytes and activated platelets or other leukocytes found at inflammatory sites. It has also been reported that this clone completely inhibits the interaction between P-Selectin and either CD4-T cells or neutrophils.
Synonyms: PSGL-1, p-selectin glycoprotein ligand-1