NCOA3 antibody

Catalog No. ABIN968949

Cited in 2+ publications. The Mouse Monoclonal anti-NCOA3 antibody (Clone 5H3) (ABIN968949) specifically detects NCOA3 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for NCOA3 antibody (ABIN968949)

Target: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCOA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5H3

Product Details anti-NCOA3 Antibody

Purpose: AIB1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human AIB1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-NCOA3 antibody (ABIN968949)

Pu, Ye, Spitz, Wang, Gu, Lippman, Hildebrandt, Hong, Minna, Roth, Yang, Wu: "Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 21, pp. 5983-91, (2012) (PubMed).

Bai, Wong: "Detection and quantification of heteroplasmic mutant mitochondrial DNA by real-time amplification refractory mutation system quantitative PCR analysis: a single-step approach." in: Clinical chemistry, Vol. 50, Issue 6, pp. 996-1001, (2004) (PubMed).

Target Details for NCOA3

Target: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Alternative Name: AIB1

Background: The poly Q polymorphism in ,AIB1 ,(amplified in breast cancer) gene is usually assessed by fragment length analysis which does not reveal the actual sequence variation. The purpose of this study is to investigate the sequence variation of poly Q encoding region in breast cancer cell lines at single molecule level, and to determine if the sequence variation is related to ,AIB1 ,gene amplification.

Molecular Weight: 155 kDa

Gene ID: 116833

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha