C-JUN antibody

Catalog No. ABIN968994

This anti-C-JUN antibody is a Mouse Monoclonal antibody detecting C-JUN in WB, IHC, ELISA, FACS and ICC. Suitable for Human, Mouse and Monkey. This Primary Antibody has been cited in 1 publication.

Quick Overview for C-JUN antibody (ABIN968994)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 5B1

Product Details anti-C-JUN Antibody

Purpose: c-Jun Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human c-Jun expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-C-JUN antibody (ABIN968994)

Jiao, Katiyar, Willmarth, Liu, Ma, Flomenberg, Lisanti, Pestell: "c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8218-26, (2010) (PubMed).

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: c-Jun

Background: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Molecular Weight: 43 kDa

Gene ID: 3725

UniProt: P05412

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins